Expert-led AI for regulatory compliance

With decades of experience guiding global regulatory compliance, 3E is now accelerating what’s possible with AI. We combine secure, highly trained generative and agentic AI technologies and our world-class, proprietary regulatory content under the watch of subject matter experts and human validation teams. The result? AI you can trust to support your business-critical decisions. Combining the power of regulatory expertise, robust data sets, and market-leading technology, 3E delivers better results for our customers.

3E puts AI to work for our customers to support:

Regulatory monitoring

3E leverages AI to enhance horizon scanning workflows, greatly reducing time needed for regulatory research - now available directly in your enterprise AI ecosystem.

Real-time, expert answers

Our AI assistant deciphers technical regulatory language and makes connections to chemical data—delivering actionable insights.

Supply chain data collection

3E supports supply chain data collection with agentic document processing and AI driven plausibility checks across supplier questionnaire responses.

GHS & DG Classification

3E enables complex classification workflows directly in customers' enterprise AI ecosystems through 3E Agent.

Compliance document generation

From SDS obtainment & indexation to Digital Product Passport (DPP) creation, 3E is accelerating the application of AI to support document analysis and outputs.

Move from compliance complexity to confident outcomes

40%+

40%+ reduction in manual monitoring effort via automated horizon scanning

70%

Up to 70% effort reduction in supplier SDS data extraction workflows

1,000+

1,000+ annual hours saved through automated portfolio reclassification

Two ways 3E puts governed AI to work for you

3E AI solutions deliver trusted intelligence in the way your teams work best: built directly into the 3E products and extended through the 3E Agent for teams working in their own AI ecosystem.

3E Agent: extend 3E's regulatory intelligence into your AI ecosystem

The 3E Agent is a new way to deliver 3E’s trusted data and expertise into your AI ecosystem, so you can do even more with 3E regulatory intelligence in your workflows. The 3E Agent complements 3E’s core software solutions with an agentic capability that extends the value of 3E content and data, securely delivering 3E intelligence into your enterprise AI environment, including Microsoft Copilot, ChatGPT Enterprise, or your custom agents, while preserving the governance, security, and traceability of the 3E platform.

The 3E Agent’s purpose-built capabilities are designed to streamline regulatory compliance workflows, reducing manual burden and decreasing risk with auditable, actionable insights.

Capabilities:

  • 3E Agent for regulatory research powers your AI environment with 3E’s verified regulatory content and analyst interpretation available in 3E Insight, reducing delays in decision-making across compliance, R&D and procurement, and improving the accuracy and speed of regulatory assessments. Work that took hours now takes minutes, with a full audit trail and no heavy lift
  • 3E Agent for classification, built for organizations that use SAP Product Compliance, enables classification of a formulation’s hazard class and transport category, comparison between two SKUs side by side across any regulatory data point, or simulation of how swapping a raw material affects compliance, all by using 3E’s curated regulatory intelligence directly in your AI workflows accompanied by plain-language verification.

3E Agent

Explore 3E Agent capabilities

Agentic AI solutions for regulatory compliance

3E Agent for Regulatory Research

3E Agent for regulatory research brings expert-curated regulatory intelligence, for over 500,000 substances, into the AI tools your organization already uses. The right answer reaches whoever needs it, in whatever department, exactly where the work happens, grounded in verified sources that hold up under audit. Decisions that once took weeks now take minutes, early enough to change the outcome.

3E is now accelerating what’s possible for regulatory content using AI.
3E Agent for Regulatory Research

Agentic AI solutions for regulatory compliance

3E Agent for Classification

Bring 3E’s GHS hazard and Dangerous Goods transport classification logic directly into the enterprise AI tools your teams already use.

Your AI ecosystem is only as strong as the data behind it. That’s why we ground every result in 3E’s authoritative regulatory intelligence instead of using generic, unverified AI outputs. With the classification capability, teams can classify, compare, and simulate with confidence, and verify the reasoning behind every answer.

3E Agent for Classification
3E Agent for Classification

View All 3E Solutions

View All 3E Solutions

Built on a foundation of trusted intelligence

From the exposure of proprietary information and trade secrets to the risks of AI outputs that include information from non-authoritative sources or hallucinations, there are many concerns that companies contend with when adopting AI for something as business-critical as regulatory compliance. That’s why 3E invests in expert-led AI model training and ensures relevant human checkpoints are in place for critical AI insights. In addition, our secure AI models have exclusive access to 3E’s world-class proprietary regulatory data and content.

3E trusted regulatory intelligence

Regulatory expertise enhanced with AI

AI is only as good as the data it’s trained on​. 3E invests in expert-led AI model training and ensures relevant human checkpoints are in place for critical outputs.​ We’ve built on domain expertise, not just algorithms. To ensure you’re receiving the best outputs, we’ve put these rigorous safeguards in place:

  • Our agentic and generative AI models access 3E’s proprietary regulatory data and content
  • Our AI models undergo extensive training from 3E regulatory experts
  • We maintain security so models do not ingest non-authoritative data or share data outside a customer’s instance
  • Our regulatory and chemical experts regularly review key outputs to maintain ongoing quality

That means you can be certain all data and intelligence it accesses is accurate, up-to-date, and expertly interpreted.

Regulatory expertise enhanced with AI

Cutting-edge innovation backed by dependable, verified governance

3E is the first major product compliance and EHS&S software company to achieve ISO 42001 certification. Audited by Prescient Security and certified under ISO/IEC 42001:2023 for its Artificial Intelligence Management System (AIMS), 3E is committed to delivering impactful AI capabilities firmly supported by governance and security you can trust.

Cutting-edge innovation backed by dependable, verified governance

Trained by experts

Our AI models undergo extensive training from 3E regulatory experts​. AI accelerates analysis, but regulatory accountability remains human. 3E solutions incorporate expert validation, quality controls, and governance checkpoints to ensure outputs are defensible, auditable, and aligned with real-world regulatory expectations. Technology amplifies expertise and should never replace it.

Trained by experts

Transparent agentic reasoning

3E’s agentic workflows are designed for clarity, not black-box automation. Outputs are traceable to source regulations, SDS data, or supplier submissions—so teams can see what changed, why it matters, and what to do next. Every recommendation is explainable and built for regulated decision-making. 

3E AI Solutions are built for enterprise environments

Security & data protection

3E AI solutions are built for enterprise environments with strong security, privacy, and governance controls. Customer data remains protected, access is controlled, and AI services operate within secure, compliant frameworks. Organizations can deploy AI confidently without compromising trust, compliance, or control.

3E offers expert-led AI solutions

Clarity in complexity. Confidence in every decision.

3E AI solutions embed trusted regulatory and chemical intelligence directly into enterprise workflows, helping organizations move from reactive compliance to confident, proactive decision-making. Built on 35+ years of expert-curated content and global regulatory depth, our solutions combine advanced automation with human oversight to deliver outcomes teams can trust. The result: faster answers, reduced risk, and AI-powered workflows designed for highly regulated industries and complex supply chains.

Faster, more confident decisions

Reduce time spent searching and interpreting regulatory, SDS, and supplier data with portfolio-aware insights that accelerate action without compromising accuracy or defensibility.

Proactive risk identification and mitigation

Surface regulatory changes, supplier gaps, and safety exposures early so teams can address risks before they escalate into compliance issues, delays, or incidents.

Scaled expertise across the organization

Embed expert regulatory and safety intelligence into everyday workflows, empowering compliance, procurement, R&D, and operations teams to act without bottlenecks or added headcount.

Governed, defensible intelligence in regulated environments

Deliver transparent, traceable outputs grounded in expert-curated data and enterprise-grade security, ensuring AI-assisted decisions remain auditable, compliant, and trusted.

Enhance your compliance with 3E

Deploy AI that understands regulatory complexity and acts on it responsibly.

Related resources

This report provides a grounded, evidence-based framework for evaluating AI in highly-regulated environments.

Report

The capability–governance gap: A 2026 evidence review of public LLMs in regulated work

May 22, 2026

The capability–governance gap: A 2026 evidence review of public LLMs in regulated work
Learn how Agentic AI transforms product stewardship workflows.

White paper

White paper: From static knowledge to dynamic intelligence: How Agentic AI transforms product stewardship and compliance

April 13, 2026

White paper: From static knowledge to dynamic intelligence: How Agentic AI transforms product stewardship and compliance
AI for regulatory compliance and data governance

Article

AI Adoption for Compliance: Expert Q&A on EHS and Product Compliance

December 8, 2025

AI Adoption for Compliance: Expert Q&A on EHS and Product Compliance
3E has achieved ISO/IEC 42001:2023 certification, independently validating how it governs AI across its product compliance solutions.

Press Release

3E strengthens trusted AI with ISO/IEC 42001 certification

August 21, 2026

3E strengthens trusted AI with ISO/IEC 42001 certification

View All 3E Resources

View All 3E Resources
  • What are 3E’s agentic AI solutions?

    3E’s agentic AI solutions are an enterprise AI deployment and intelligence layer that powers real-time regulatory decision-making and compliance workflow automation using live, expert-curated regulatory data and transparent agentic reasoning. 

    Unlike generic AI tools, 3E’s solutions are purpose-built for high-stakes domains such as chemical safety, SDS authoring, product compliance, regulatory monitoring, and supply chain risk management — where accuracy, traceability, and human oversight are non-negotiable. 

    3E transforms AI from isolated experimentation into governed, production-ready services embedded directly into compliance workflows. 

  • What is 3E Agent?

    The 3E Agent offers a new way to deliver 3E’s trusted data and expertise into a customer’s AI ecosystem, so they can do even more with 3E regulatory intelligence in their workflows. It complements 3E’s core software solutions with an agentic capability that extends the value of our content and data. Imagine your own AI agent that combines 3E’s proprietary regulatory content, plus an agentic reasoning engine to apply that knowledge like a real expert, but at a speed and scale never before possible.

  • How can I be sure I can trust 3E's AI reasoning?

    Critical decisions remain transparent, explainable, and auditable thanks to human-over-the-loop (HOTL) governance. Experts review and validate outputs where required — ensuring AI accelerates work without eliminating accountability. Also, our decision-making models show you their process and how they come to the decisions they make so you can be sure you agree with how the AI came to its conclusion and you know exactly what source is cited. 

  • Which organizations benefit most from agentic AI solutions for compliance?

    3E’s agentic AI solutions are built for organizations where regulatory accuracy and safety directly impact revenue and risk. 

    • EHS and Product Stewardship leaders managing complex portfolios 
    • Regulatory Affairs teams navigating global obligations 
    • Supply chain and procurement teams assessing material risk 
    • Sustainability professionals managing evolving frameworks 
    • CIOs and CTOs deploying enterprise-grade AI under strict governance 
    • R&D and innovation teams anticipating regulatory constraints early 
  • Does 3E AI connect to Copilot?

    Yes. The 3E Agent is built to integrate into enterprise AI ecosystems, including environments powered by Copilot and other AI platforms.

    Rather than replacing your existing tools, 3E connects trusted regulatory, safety and supplier intelligence into them. That means your Copilot can operate with authoritative, portfolio-aware context instead of relying only on general language capabilities.

    In practice, this allows teams to:

    • Ask compliance questions inside their existing AI environment

    • Surface regulatory impact tied to their actual products and materials

    • Embed safety and supplier intelligence directly into enterprise workflows

    • Maintain governance, traceability and access controls

    The result is AI that works inside the systems your teams already use — powered by trusted 3E intelligence.

  • Why use 3E instead of ChatGPT for regulatory compliance?

    With the 3E Agent, you can access expert-curated regulatory intelligence directly from your ChatGPT Enterprise instance.

    3E’s AI solutions are purpose-built for regulated compliance work, grounded in continuously maintained regulatory data, your product portfolio, and your SDS library. A general-purpose assistant on its own produces plausible answers. With the 3E Agent, that same assistant answers from your data, with domain-specific grounding, portfolio awareness, and audit-ready traceability.

    ChatGPT is a powerful general-purpose tool for drafting, summarizing and research. Many teams use it for productivity. The difference is what it is grounded in.

    ChatGPT does not inherently understand:

    • Your product portfolio

    • Your SDS library

    • Your supplier data

    • Jurisdiction-specific regulatory nuance

    • Enterprise compliance workflows

    3E embedded AI solutions and the 3E Agent operate on expert-curated regulatory intelligence, validated safety data, and structured supplier information. They are portfolio-aware and integrated into compliance workflows: not just generating text, but supporting execution.

    That means:

    • Regulatory impact is tied to your actual products

    • Safety guidance reflects your SDS data

    • Supplier compliance gaps are prioritized automatically

    • Outputs are traceable and aligned to audit expectations

  • My company has already built an AI ecosystem. Isn't 3E just duplicating that effort?

    No — the 3E Agent is designed to strengthen and extend your existing AI ecosystem, not replace it.

    Most enterprise AI strategies focus on infrastructure: model orchestration, data pipelines, copilots, security layers and governance controls. That foundation is essential. What it typically does not include is deeply structured, continuously maintained regulatory, safety and supplier intelligence — converted into machine-operable logic and validated for compliance workflows.

    3E fits into your architecture as the intelligence and execution layer for regulated domains.

    Instead of duplicating your AI investment, 3E:

    • Connects authoritative regulatory and safety data into your existing AI environment

    • Provides portfolio-aware context across products, materials and suppliers

    • Embeds structured compliance logic your internal teams would otherwise have to build

    • Operates within your governance, security and integration standards

    Think of it this way:

    • Your AI ecosystem provides the platform and orchestration.

    • 3E provides the domain-specific intelligence, validation and regulatory execution layer.

    You could build that regulatory and safety layer internally — but it would require ongoing global content maintenance, subject matter expertise and continuous testing against evolving regulations.

    With 3E, you accelerate your AI roadmap by plugging trusted, enterprise-ready compliance intelligence into the ecosystem you have already built — without recreating decades of regulatory expertise from scratch.

Speak with an AI for product compliance expert

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Explore 3E Agent capabilities

Agentic AI solutions for regulatory compliance

3E Agent for Regulatory Research

3E Agent for regulatory research brings expert-curated regulatory intelligence, for over 500,000 substances, into the AI tools your organization already uses. The right answer reaches whoever needs it, in whatever department, exactly where the work happens, grounded in verified sources that hold up under audit. Decisions that once took weeks now take minutes, early enough to change the outcome.

3E is now accelerating what’s possible for regulatory content using AI.
3E Agent for Regulatory Research

Agentic AI solutions for regulatory compliance

3E Agent for Classification

Bring 3E’s GHS hazard and Dangerous Goods transport classification logic directly into the enterprise AI tools your teams already use.

Your AI ecosystem is only as strong as the data behind it. That’s why we ground every result in 3E’s authoritative regulatory intelligence instead of using generic, unverified AI outputs. With the classification capability, teams can classify, compare, and simulate with confidence, and verify the reasoning behind every answer.

3E Agent for Classification
3E Agent for Classification

View All 3E Solutions

View All 3E Solutions

Explore related products

Chemical & Workplace Safety

3E Protect

3E Protect is an SDS management software and chemical safety platform giving enterprises access to a 20M+ global Safety Data Sheet library, inventory management, hazard screening, regulatory intelligence, and 24/7/365 live EHS hotline support — no per-SDS fees, no per-user limits. Backed by 35+ years of regulatory expertise and trusted by 5,000+ customers globally, 3E Protect transforms static SDS access into portfolio-aware safety intelligence embedded in ERP, EHS, and enterprise AI workflows.

3E Protect
3E Protect

Chemical & Workplace Safety

3E Insight

Generic regulatory feeds create noise. Missed regulations create risk. 3E Insight cuts through both — delivering intelligence that’s filtered, prioritized, and contextualized to your specific product portfolio. Regulatory, R&D, EHS, and sustainability teams can effortless monitor REACH, TSCA, CLP, GHS, OSHA HazCom, and 3,200+ regulatory lists across 150+ countries. Always know what’s changed, what it means for your products, and what to do next.  

 

3E Insight delivers intelligence that's filtered, prioritized, and contextualized to your specific product portfolio
3E Insight

Supply Chain Visibility

3E Exchange

3E Exchange is a supply chain data collection and compliance platform that centralizes supplier surveys, validates regulatory data, and manages product compliance, and sustainability workflows in one system. It supports 200+ regulatory lists — including EU REACH, RoHS, TSCA, California Prop 65, conflict minerals, and SCIP — and provides agentic workflows to streamline supplier document processing, supplier data collection, and portfolio analysis.

3E Exchange
3E Exchange

View All 3E Solutions

View All 3E Solutions